A scaling profile can be changed using CLI only when all ESA-VMs in a NAT group are removed from the configuration.
For example, in the following case, transitioning from profile2 to profile1 is not possible until esa-vm 1/1 is removed from the CLI:
config
isa
nat-group 1
esa-vm 1/1
scaling-profile profile2
config>isa>nat-group# scaling-profile profile1
MINOR: BBGRPMGR #1052 Cannot change scale-profile with MDAs or ESA-VMs provisioned